Skip to main content


Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Figure 2 | Respiratory Research

Figure 2

From: Differential regulation of cell functions by CSD peptide subdomains

Figure 2

Effects of CSD and its subdomains on Normal and SSc monocyte migration in vitro. Normal monocytes (A) were isolated from healthy donors, SSc monocytes (C) were isolated from SSc patients. The migration of these cells and Normal monocytes pretreated with TGFβ (B) toward CXCL12 was quantified in the presence of 5 μM of CSD or the indicated subdomains of CSD as described in the Methods. The Antennapedia Internalization Sequence alone was routinely used as the Control peptide; when tested scrambled CSD attached to the Antennapedia Internalization Sequence gave similar results. Each symbol represents the results obtained with cells from an individual donor.

Back to article page