Figure 2
From: Myofibroblast expression in airways and alveoli is affected by smoking and COPD
Number of subjects expressing immunoreactivity for α-SMA, Tn-C or EDA-Fn within widened alveolar tips and airways. Image 2A represents the number of widened alveolar tips, which were positive either for α-SMA (black), Tn-C (grey) or EDA-Fn (white) counted per area of peripheral lung tissue slide (cm2) in different patient groups. Stars indicate p < 0.001 when compared to non-smokers. 2B shows the total number of small airways i.e. bronchioles in the tissue slide. A star indicates p < 0.05 when compared to non-smokers. 2C shows relative expression (weighted mean) of α-SMA positive, spindle-shaped cells in the subepithelial area of bronchioles. A star indicates p < 0.05 when compared to non-smokers. 2D illustrates the area of α-SMA positive cells (mm2) per length of bronchial epithelium (mm). Stars indicate p < 0.05 when compared to COPD. Standard deviations are shown.