Figure 2
From: HTR4 gene structure and altered expression in the developing lung
Immunohistochemistry of 5-HT 4 R in COPD lung tissue. Weak 5-HT4R staining was found in the nuclei and cytoplasm of pneumoctyes in the alveolar regions of all COPD samples (a-c). In the bronchial epithelium COPD1 had weak nuclear staining (g), COPD2 had moderate nuclear and cytoplasmic staining (h) whilst COPD3 was negative for the 5-HT4R protein (i). All isotype controls were negative (d-f and j-l). X40 magnification.