Figure 6

Comparison of cytokines produced by mDC subsets in response to RSV and poly I:C. ( A ) BDCA-1⁺ and ( B ) BDCA-3⁺ mDCs were isolated and incubated with RSV, poly I:C or media alone for 40 hours. Cytokine and chemokine levels were measured in cell-free supernatant by multiplex assay. Data represents the mean + SEM of the fold change in cytokine production by treated cells as compared to untreated cells of the same type from 5 donors. Linear data is reported on a logarithmic scale. The dotted line represents a 2 fold induction. *= Statistically significant (p≤0.05) difference in cytokine production by RSV-infected mDCs as compared to poly I:C-activated mDCs by student’s paired t-test.