Figure 4

Comparison of costimulatory molecule expressed by mDC subsets in response to RSV and poly I:C. ( A ) BDCA-1⁺ and ( B ) BDCA-3⁺ mDCs were incubated in media alone, infected with RSV at a MOI=5, or activated with poly I:C for 40 h. Bar graphs represent the change in mean fluorescent intensity (MFI) of expression by infected cells over uninfected cells (mean + SEM of 5 donors). Linear data is reported on a logarithmic scale. The dotted line represents a 2 fold induction. *=statistically significant difference (p≤0.05) in expression by RSV-infected mDCs as compared to poly I:C-activated mDCs by student’s paired t-test.