Figure 3
From: NF-κB activation in myeloid cells mediates ventilator-induced lung injury
Decreased ventilator-induced lung damage in IKKβ△myemice. High tidal volume ventilation induced total number of cells in BALF (A), protein concentration in BALF (B), and pulmonary microvascular permeability (C) in WT mice but not in IKKβ△mye mice. However, there was more neutrophil sequestration in the IKKβ△mye mice (D). *P<0.05, **P<0.01, ***P<0.001. (E). E.coli. LPS stimulation-induced activation of alveolar macrophages was decreased in IKKβ△mye mice when compared with WT mice.