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Table 3 Discrimination of the various multivariate models in the identification of COPD in subgroups of asymptomatic and symptomatic subjects

From: Diagnosis of chronic obstructive pulmonary disease in lung cancer screening Computed Tomography scans: independent contribution of emphysema, air trapping and bronchial wall thickening

 

Model

C-index (95% CI)

  

Asymptomatics

Symptomatics

1

Baseline model *

0.674 (0.625 -0.722)

0.634 (0.589 - 0.679)

2

+ CT-BWT

0.739 (0.695 - 0.783)

0.764 (0.725 - 0.803)

3

+ CT air trapping

0.737 (0.693 - 0.780)

0.794 (0.759 - 0.829)

4

+ CT emphysema

0.753 (0.707 – 0.800)

0.806 (0.771 - 0.841)

5

+ CT-BWT

0.771 (0.730 – 0.813)

0.821 (0.788 – 0.855)

+ CT air trapping

6

+ CT emphysema

0.782 (0.740 - 0.824)

0.872 (0.844 - 0.899)

+ CT air trapping

7

+ CT emphysema

0.828 (0.790 – 0.866)

0.886 (0.859 - 0.912)

+ CT-BWT

8

+ CT emphysema

0.832 (0.795 – 0.869)

0.905 (0.881 - 0.929)

 

+ CT-BWT

  
 

+ CT air trapping

  
  1. * Model including age, body mass index, smoking status and packyears of smoking history; 95% CI = 95th percentile confidence interval; CT-BWT = Quantitatively assessed bronchial wall thickness.
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Respiratory Research

ISSN: 1465-993X

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