Figure 1

Analysis of prognostic value of baseline serum CCL17. A: Receiver operating curve analysis of baseline CCL17 levels using the first episode of AE as an endpoint (p = 0.02, AUC = 0.77). B: Box and whisker plots of baseline concentrations of CCL17 in AE and NAE groups, and healthy volunteers (HV) as a reference. The dotted line represents the cutoff value for predicting AE. C: The incidence of acute exacerbations grouped by baseline serum concentrations. The black line represents the chronic HP patients with baseline serum CCL17 concentrations above 285 pg/ml. The gray line represents the chronic HP patients with baseline serum CCL17 concentrations under 285 pg/ml (log rank test, p = 0.0006).