Figure 1
From: Maresin-1 reduces the pro-inflammatory response of bronchial epithelial cells to organic dust
Effects of MaR1 pretreatment on HDE-induced IL-6 and IL-8 release 24 hours following HDE treatment in bronchial epithelial cells. BEAS-2B cells were pretreated with 0, 1, 10, 100, or 200 nM MaR1 for 1 hour, then treated with 5% HDE. At 24 hours post HDE treatment, cell supernatant was collected and assayed for A) IL-6 and B) IL-8 levels, using ELISAs. ***p < 0.001 compared to 5% HDE. Data is representative of 4 separate experimental replicates (biological replicates), with two technical replicates per experiment.