Changes in transcriptome of native nasal epithelium expressing F508del-CFTR and intersecting data from comparable studies

Table 1 Identity of nasal epithelial cell samples used in microarray analysis

Individual	Gender	Age (yr)	% inflamm. cells	FVC (% of expected)	FEV1 (% of expected)
CF (F508del homozygous)
BC	F	9	5.1	1.70 L (88.7%)	1.39 L (84.6%)
FC	M	17	9.8	4.16 L (90.6%)	3.36 L (88.5%)
JF	M	16	6.5	2.65 L (60.7%)	1.43 L (39.7%)
PM	F	10	4.2	0.60 L (38.3%)	0.60 L (43.8%)
SS	F	18	4.3	3.00 L (78.5%)	2.28 L (70.7%)
*Mean*	-	14	5.98
non CF
AC	F	16	1.6	n/a	n/a
BR	M	16	3.7	n/a	n/a
FR	M	14	4.4	n/a	n/a
JR	M	14	8.1	n/a	n/a
SP	F	14	5.7	n/a	n/a
*Mean*	-	14.8	4.7

Neither age (p = 0.69, student’s t test) nor percentage of inflammatory cells per sample (p = 0.42, student’s t test) showed any significant difference between groups. Data on lung function were obtained for CF patients only: percentage of expected function for relevant age group shown in brackets.

ISSN: 1465-993X