Figure 6

Demonstration of pathway enrichment in present study by GSEA. GSEA enrichment plots showing significant enrichment (ES significant at p < 0.05 level) of genesets for A) positive and B) negative regulation of cell proliferation, C) ESR1 targets, D) cell proliferation and E) defence response for the CF phenotype, and F) motor activity for the non CF phenotype. The lower panel shows G) significant enrichment of the NF-kB pathway in the CF phenotype and non-significant skews of H) antigen presentation pathway genes in the non CF phenotype and I) protein ubiquitination genes in the CF phenotype.