| PBS (8) | CD34+ Fresh (3) | CD34+ Basic (12) | CD34+ Dex (8) |
---|
Body wt (g)
| 26.37 ± 2.76 | 21.00 ± 2.95* | 25.50 ± 4.43 | 23.01 ± 3.29* |
V(lu) (μl)
| 669 ± 161 | 595 ± 105 | 814 ± 153* | 738 ± 113 |
A
A
(ae/lu)
| 21.3 ± 4.7 | 20.2 ± 3.0 | 21.1 ± 3.1 | 24.0 ± 4.9 |
V(ae) (μl)
| 136 ± 23 | 118 ± 12 | 170 ± 31* | 177 ± 43* |
V(ae)/BW (μl/g)
| 5.33 ± 0.48 | 5.69 ± 0.82 | 6.84 ± 1.35** | 7.45 ± 1.92** |
- Animals were treated with freshly isolated CB-CD34+ cells (0.5 x 106 cells/pup) or CB-CD34+ cells expanded in basic medium or DEX medium (1-2 x 106 cells/pup). Sham controls received equal volume PBS.
- Values represent mean ± SD of (n) animals per group.
- V(lu): lung volume; AA(ae/lu): areal fraction of air-exchanging parenchyma; V(ae): volume of air-exchanging parenchyma.
- *: P < 0.05; **: P < 0.01 versus PBS-treated sham controls.
- (Student-t test).