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Table 3 Characteristics of surgical lung tissue subjects

From: Smoking decreases the response of human lung macrophages to double-stranded RNA by reducing TLR3 expression

Group Smokers with COPD Smokers without COPD pvalue
Subjects, n 18 7  
Sex ratio, M/F 10/8 5/2 0.49
Age, years (SD) 61.8 (9.4) 54.4 (9.1) 0.74
Smoking, pack-years (SD) 60.3 (41.4) 44.5 (23.9) 0.47
Smoking status (Former/Current) 4/14 3/4 0.11
FEV1, % pred. (SD) 41.8 (27.7) 95.4 (11.2) 0.0008
FEV1/FVC% (SD) 42.5 (18.6) 76.0 (5.2) 0.0002
ICS use (yes/no) 12/6 1/6 0.02
  1. ICS Inhaled Corticosteroid Use, M Male, F Female. Data are represented as mean (SD), ratio of current smokers to former smokers, or fraction of ICS users (yes/no). All FEV1 values are pre-bronchodilator. p values calculated using Mann Whitney test.