Figure 5
From: Apoptosis inhibitor of macrophage (AIM) expression in alveolar macrophages in COPD
Hypothetical model of involvement of AIM in COPD pathogenesis. AIM expression AM in response to CSE exposure may enhance accumulation of AM as a pathogenic sequence for COPD development through prolonged inflammation. Definition of abbreviations: AIM = apoptosis inhibitor of macrophage, AM = alveolar macrophage, Bcl-xL = anti-apoptotic B cell lymphoma leukemia COPD = chronic obstructive pulmonary disease.