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Figure 6 | Respiratory Research

Figure 6

From: Genetic replacement of surfactant protein-C reduces respiratory syncytial virus induced lung injury

Figure 6

SP-C deficiency increases the type II cell cytokine response to RSV infection and TLR3 challenge. Cytokine levels were measured in the culture media of Sftpc +/+ and -/- type II cells challenged with the TLR3 ligand poly I:C (Panel A) or by RSV infection (Panel B). Basal levels of cytokine expression were elevated in the media from Sftpc -/- type II cells and the response to poly I:C or virus was increased relative to the Sftpc +/+ cells. Cytokine concentrations are in pg/ml (x axis). N = 3.

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