Table 1 Differential gene expression between baseline COPD pBECs and healthy control pBECs

Protease and Antiproteases

MMP10

Matrix metallopeptidase 10

2.94

0.0029

PI3

Peptidase inhibitor 3 (Elafin)

2.22

0.0287

ADAM19

ADAM metallopeptidase domain 19

2.13

0.0090

Innate immunity

S100A8

S100 calcium binding protein A8

2.63

0.0189

S100A9

S100 calcium binding protein A9

2.32

0.0143

Epithelial cell related processes

KRT6C

Keratin 6C

10.01

0.0002

RHCG

Rh family, C glycoprotein

2.51

0.0033

CNFN

Cornifelin

2.23

0.0213

SPRR2E

Small proline-rich protein 2E

2.15

0.0017