Figure 1

MRI images from a control subject, a mild-to-moderate COPD patient and a severe COPD patient. A line has been placed over the region of the hippocampus in one hemisphere. A = control subject; B = mild-to-moderate COPD patient; C = severe COPD patient; A_R = the right hippocampus of control subject; A_L = the left hippocampus of control subject; B_R = the right hippocampus of mild-to-moderate COPD patient; B_L = the left hippocampus of mild-to-moderate COPD patient; C_R = the right hippocampus of severe COPD patient; C_L = the left hippocampus of severe COPD patient.