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Table 3 Effect of ozone on FEF 25-75 , according to the number of risk alleles and vitamin C &

From: Ozone exposure, vitamin C intake, and genetic susceptibility of asthmatic children in Mexico City: a cohort study

 

30–105 mg/day

>105–477 mg/day

 

Risk Alleles

n

Coeff(95% CI)

n

Coeff(95% CI)

Diet effectπ

All asthmatics

1 to 3

30

24.0 (−50.0, 98.1)

73

27.0 (−16.5, 70.5)

3.0 (−82.2, 88.2)

4 to 6

30

−58.8 (−122.3, 0.1) £

66

−16.8 (−49.7, 16.1)

42.0(−24.0, 108.0)

Genotype effect Ω

 

−82.8 (−180.0, 15.0) £

 

−43.8 (−98.4, 11.4)

 

Persistent asthmatics

1 to 3

18

19.2 (−67.8, 106.2)

50

15.6 (−35.0, 66.2)

−3.6 (−105.6, 98.4)

4 to 6

19

−97.2 (−185.4, -9.0) €

50

−18.6 (−58.6, 21.4)

78.6 (77.1, 80.1) £

Genotype effect

 

−116.4 (−118.4, -114.4) £

 

−34.2 (−98.4, 30.0)

 
  1. Models were adjusted for gender, age, BMI, height, chronological time, cohort, use of bronchodilator, and minimum temperature. All asthmatics: n = 199 and 3842 repeated measures; persistent (mild, moderate or severe) asthmatics: n = 137 and 2715 repeated measures.
  2. € p ≤ 0.05; £ 0.05 < p ≤ 0.1; Ω Genotype effect is defined to be the change in response produced by a change in the level of genotype.
  3. Π Diet effect is defined to be the change in response produced by a change in the level of diet intake. &FEF25-75 is reported as ml/s per 1-h 60 ppb on the day prior to spirometric test.
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Respiratory Research

ISSN: 1465-993X

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