Table 1 Clinical characteristics of the total cohort and after stratification for CAC
From: Associations between COPD related manifestations: a cross-sectional study
Total cohort | CAC = 0 | 0 < CAC ≤ 400 | CAC > 400 | p-value | |
|---|---|---|---|---|---|
Number of subjects | 119 | 14 | 41 | 64 | |
Age, yrs | 67.8 ± 7.3 | 58.6 ± 6.3 | 66.1 ± 6.2 | 70.8 ± 6.2 | <0.001 |
Male, n (%) | 79 (66) | 7 (50) | 24 (59) | 48 (75) | 0.03 |
FEV1, % predicted | 46.0 ± 17.5 | 44.2 ± 13.7 | 43.8 ± 17.4 | 47.9 ± 18.3 | 0.47 |
FVC, % predicted | 74.4 ± 20.6 | 72.6 ± 14.2 | 74.4 ± 21.0 | 74.8 ± 21.7 | 0.94 |
FEV1/FVC ratio | 47.1 ± 12.3 | 46.9 ± 10.7 | 44.9 ± 13.5 | 48.6 ± 11.9 | 0.33 |
BMI, kg/m2 | 25.8 ± 5.5 | 25.6 ± 5.9 | 25.7 ± 5.2 | 25.9 ± 5.6 | 0.98 |
Distance walked, m | 369.1 ± 112.2 | 406.6 ± 105.2 | 385.9 ± 105.0 | 349.8 ± 116.1 | 0.16 |
Pack-years of smoking, n | 45.4 ± 20.5 | 44.4 ± 20.2 | 44.6 ± 21.7 | 46.2 ± 20.0 | 0.91 |
Heart rate, beats/min | 74.0 ± 13.0 | 71.5 ± 10.1 | 73.4 ± 12.0 | 74.9 ± 14.2 | 0.65 |
Blood pressure systolic, mmHg | 142.2 ± 23.9 | 127.7 ± 16.5 | 136.2 ± 20.3 | 149.2 ± 25.0 | 0.001 |
Blood pressure diastolic, mmHg | 79.9 ± 11.3 | 76.6 ± 11.5 | 78.0 ± 9.2 | 81.9 ± 12.1 | 0.11 |
Hypertension, n (%) | 30 (25) | 0 (0) | 7 (17) | 23 (36) | 0.002 |
Ischemic heart disease, n (%) | 22 (19) | 0 (0) | 4 (10) | 18 (28) | 0.003 |
Diabetes, n (%) | 7 (6) | 0 (0) | 2 (5) | 5 (8) | 0.25 |
TAC, median (min-max) | 1540 (0–20828) | 262 (0–4237) | 1125 (3–8606) | 3475 (0–20828) | <0.001 |
PWV, m/s | 8.90 ± 1.63 | 8.35 ± 1.36 | 9.18 ± 1.54 | 8.86 ± 1.72 | 0.31 |
PI-950, median in % (min-max) | 6.89 (0.12–43.2) | 17.1 (0.12–39.0) | 5.32 (0.12–43.2) | 6.86 (0.27–38.6) | 0.81 |
15th percentile, HU | -921.9 ± 27.8 | -919.9 ± 38.3 | -924.2 ± 29.7 | -920.8 ± 24.1 | 0.82 |
Bone attenuation, HU | 138.1 ± 35.5 | 162.2 ± 37.6 | 141.8 ± 31.9 | 130.4 ± 35.0 | 0.006 |