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Table 1 Clinical characteristics of the total cohort and after stratification for CAC

From: Associations between COPD related manifestations: a cross-sectional study

 

Total cohort

CAC = 0

0 < CAC ≤ 400

CAC > 400

p-value

Number of subjects

119

14

41

64

 

Age, yrs

67.8 ± 7.3

58.6 ± 6.3

66.1 ± 6.2

70.8 ± 6.2

<0.001

Male, n (%)

79 (66)

7 (50)

24 (59)

48 (75)

0.03

FEV1, % predicted

46.0 ± 17.5

44.2 ± 13.7

43.8 ± 17.4

47.9 ± 18.3

0.47

FVC, % predicted

74.4 ± 20.6

72.6 ± 14.2

74.4 ± 21.0

74.8 ± 21.7

0.94

FEV1/FVC ratio

47.1 ± 12.3

46.9 ± 10.7

44.9 ± 13.5

48.6 ± 11.9

0.33

BMI, kg/m2

25.8 ± 5.5

25.6 ± 5.9

25.7 ± 5.2

25.9 ± 5.6

0.98

Distance walked, m

369.1 ± 112.2

406.6 ± 105.2

385.9 ± 105.0

349.8 ± 116.1

0.16

Pack-years of smoking, n

45.4 ± 20.5

44.4 ± 20.2

44.6 ± 21.7

46.2 ± 20.0

0.91

Heart rate, beats/min

74.0 ± 13.0

71.5 ± 10.1

73.4 ± 12.0

74.9 ± 14.2

0.65

Blood pressure systolic, mmHg

142.2 ± 23.9

127.7 ± 16.5

136.2 ± 20.3

149.2 ± 25.0

0.001

Blood pressure diastolic, mmHg

79.9 ± 11.3

76.6 ± 11.5

78.0 ± 9.2

81.9 ± 12.1

0.11

Hypertension, n (%)

30 (25)

0 (0)

7 (17)

23 (36)

0.002

Ischemic heart disease, n (%)

22 (19)

0 (0)

4 (10)

18 (28)

0.003

Diabetes, n (%)

7 (6)

0 (0)

2 (5)

5 (8)

0.25

TAC, median (min-max)

1540 (0–20828)

262 (0–4237)

1125 (3–8606)

3475 (0–20828)

<0.001

PWV, m/s

8.90 ± 1.63

8.35 ± 1.36

9.18 ± 1.54

8.86 ± 1.72

0.31

PI-950, median in % (min-max)

6.89 (0.12–43.2)

17.1 (0.12–39.0)

5.32 (0.12–43.2)

6.86 (0.27–38.6)

0.81

15th percentile, HU

-921.9 ± 27.8

-919.9 ± 38.3

-924.2 ± 29.7

-920.8 ± 24.1

0.82

Bone attenuation, HU

138.1 ± 35.5

162.2 ± 37.6

141.8 ± 31.9

130.4 ± 35.0

0.006

  1. Results are presented as mean ± standard deviation unless otherwise indicated.
  2. PWV was assessed in 104 subjects.
  3. BMI body mass index, CAC coronary artery calcium, FEV 1 forced expiratory volume in 1 second, FVC forced vital capacity, HU hounsfield unit, PI pixel index, PWV pulse wave velocity, TAC thoracic aortic calcium.