Figure 8
From: Nicotine exposure during differentiation causes inhibition of N-myc expression
Nicotine exposure during differentiation decreases cell counts and increases doubling time. nhpESC were differentiated in the presence or absence of 100 nM nicotine. Doubling time was measured by cell counts through passage 5 after differentiation. Data is expressed as cell counts at passage five, with error bars demonstrating standard deviation, p < 0.001 (upper panel), and this data was converted into doubling time, show in hours (lower panel). Cells differentiated in the presence of nicotine had a higher doubling time, which was significantly slower than control starting at passage 5.