Figure 5
From: Nicotine exposure during differentiation causes inhibition of N-myc expression
Differentiated nhpESC are more similar to primary NHP fibroblasts than their parental cells with respect to global gene expression analysis. Affymetrix gene array analysis was done to assay global gene expression patterns. The lines were then grouped according to similarities in gene expression using cluster analysis. This shows that in vitro differentiated fibroblast-like cells (4706D, 3106D, 2706D) are more similar to primary adult lung fibroblasts (222) than with the parental cells from which they were derived (4706UN, 2706UN, 3106UN).