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Table 1 Literature overview of volatile organic compounds found in in vitro and in vivo studies in samples with Pseudomonas aeruginosa

From: Detection of Pseudomonas aeruginosa in sputum headspace through volatile organic compound analysis

In vitro

Volatiles

reference

 

acetaldehyde, acetic acid, acetone, ammonia, ethanol, dihydrogen sulfide, dimethyl disulfide, dimethyl sulfide, methyl mercaptan

[21]

 

ammonia, hydrogen cyanide, methyl mercaptan

[22]

 

hydrogen cyanide

[23]

 

2-aminoacetophenone, ammonia, ethanol, formaldehyde, hydrogen sulfide, isoprene, methyl mercaptan, trimethylamine

[24]

 

2-aminoacetophenone, 2-pentanone, 4-methylphenol, acetic acid, acetone, acetonitrile, ethanol, ethylene glycol, indole

[25]

 

1-butanol, 1-undecene, 2-butanone, 2-heptanone, 2-nonanone, 2-undecanone, 3-methyl-1-butanol, toluene

[26]

 

2-aminoacetophenone

[27]

 

1-undecene, 2-aminoacetophenone, 2-butanone, 2-nonanone, 2-undecanone, 3-methyl-1-butanol, 4-methyl-quinazoline, butanol, dimethyl disulfide, dimethyl trisulfide, methyl mercaptan, toluene

[28]

 

2-propanol

[29]

 

2-aminoacetophenone, dimethyl disulfide, dimethylpyrazine, dimethyl sulfide, undecene

[30]

 

Methyl thiocyanate

[20]

In vivo

  

breath

hydrogen cyanide

[18]

breath

Methyl thiocyanate

[20]

breath

2-propanol

[29]

sinus mucus

2-aminoacetophenone, 2-methylbutyric acid, 3-hydroxy-2-butanone, acetamide, acetic acid, acetone, dimethyl disulfide, dimethyl sulfide, dimethylsulfone, hydrogen sulfide, indole, isovaleric, phenol, propanoic acid

[30]

sputa

1-heptene, 2-nonanone, 2,4-dimethyl-heptene, 3-methyl-1-butanol, limonene

[31]