Table 2 Cell features that are decisive for lysosomal Fe 2+ -reactivity in human lung macrophages
From: Leaky lysosomes in lung transplant macrophages: azithromycin prevents oxidative damage
ASSAYS | Lung transplant recipients without AZM (n = 5) | Lung transplant recipients with AZM (n = 3) | Healthy control patients (n = 7) |
|---|---|---|---|
Golde Index | 55.8 ± 37.2 (0.024) | 71.7 ± 15.1 (0.013) | 8.2 ± 11.9 |
Cellular iron (ng/mg protein) | 11.2 ± 7.8 (0.048) | 29.6 ± 23.6 (0.028) | 4.5 ± 2.5 |
H-ferritin (ng/mg protein) | 94.2 ± 76.3 (0.136) | *Not done | 29.8 ± 19.8 |
GSH (ng/mg protein) | 40.8 ± 20.1 (0.890) | 28.3 ± 3.9 (0.012) | 39.9 ± 8.1 |