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Table 2 Cell features that are decisive for lysosomal Fe 2+ -reactivity in human lung macrophages

From: Leaky lysosomes in lung transplant macrophages: azithromycin prevents oxidative damage

ASSAYS Lung transplant recipients without AZM (n = 5) Lung transplant recipients with AZM (n = 3) Healthy control patients (n = 7)
Golde Index 55.8 ± 37.2 (0.024) 71.7 ± 15.1 (0.013) 8.2 ± 11.9
Cellular iron (ng/mg protein) 11.2 ± 7.8 (0.048) 29.6 ± 23.6 (0.028) 4.5 ± 2.5
H-ferritin (ng/mg protein) 94.2 ± 76.3 (0.136) *Not done 29.8 ± 19.8
GSH (ng/mg protein) 40.8 ± 20.1 (0.890) 28.3 ± 3.9 (0.012) 39.9 ± 8.1
  1. Data are presented as the means ± 1 SD. P-value vs. healthy control patients is indicated. *The assay was not performed because of the size of the sample.