Figure 1From: Nitric oxide-induced eosinophil apoptosis is dependent on mitochondrial permeability transition (mPT), JNK and oxidative stress: apoptosis is preceded but not mediated by early mPT-dependent JNK activationSNAP induces late apoptosis in GM-CSF-treated eosinophils. Eosinophils were incubated in the presence or absence of 1 mM SNAP, 1 mM penicillamine and/or 10 pM GM-CSF for the indicated times. Apoptosis was measured by DNA fragmentation assay. *** indicates p < 0.001 as compared with cells treated with GM-CSF and penicillamine at the corresponding time-point. Mean ± SEM is shown from six independent experiments.Back to article page