Figure 4

Distribution of the total Wnt7B reactivity at the EF, SE, and I site categories for patients with FVCs >80% (normal), 50-80% (intermediate impairment), or <50% (severe impairment). Normal patients had minimal Wnt7B reactivity, most with a median total area reactivity of “0” (a). Patients with impaired FVCs had many more reactive sites than controls, although those with intermediate and severe impairment were not different (see Tables 2 and 3). Notably, the median of the mean total of reactivity was greatest in the SE sites that were <50 μm² (b-c).