Figure 4

Dose response effect of pretreatment with inhaled heparin tetrasaccharide on antigen-induced early and late airway responses (EAR and LAR) in "Dual Responder" sheep. Data are shown as antigen-induced % change in specific lung resistance (SR_L) ± SE without (solid circles) and after pretreatment (open circles) with inhaled tetrasaccharide (0.03 mg/kg, n = 5); 0.06 mg/kg, n = 6); and 0.125 mg/kg, n = 5). BSL = Baseline.