Figure 5
From: Inhibition of Pyk2 blocks lung inflammation and injury in a mouse model of acute lung injury
Effect of Pyk2 inhibition on production of MIP-2 and KC in the BALF of LPS-challenged mice. Mice were given an i.p. administration of 10 mg/kg TAT-Pyk2-CT 1 h prior to an i.t. administration of LPS. BALF was collected at 18 h following LPS challenge to analyze the concentration of MIP-2 and KC. The values presented were the means ± SEM (n = 4 for control, 12 for LPS alone, 9 for TAT-Pyk2-CT + LPS, and 10 for TAT-GFP + LPS). #P < 0.05 vs. control group; *P < 0.05 vs. LPS alone group.