Figure 3From: Mechanical ventilation with high tidal volumes attenuates myocardial dysfunction by decreasing cardiac edema in a rat model of LPS-induced peritonitisMyocardial function ex vivo (LPS = lipopolysaccharide; LTV = low tidal volume, HTV = high tidal volume). A. Left ventricular systolic pressure decreased by LPS treatment (P < 0.001) and increased Vt-dependently (P = 0.04). B. Left ventricular developed pressure decreased by LPS treatment (P < 0.001). C. Left ventricular + dP/dtmax decreased after LPS treatment (P < 0.001) and increased Vt-dependently (P = 0.025). D. Left ventricular time constant of relaxation tau increased after LPS treatment (P = 0.001.) E. Left ventricular - dP/dtmin increased after LPS treatment (P < 0.001). F. Maximal coronary flow decreased after LPS treatment (P < 0.001).Back to article page