Table 3 Diagnostic test performance of GOLD and LLN with the expert panel as the reference test
GOLD | LLN: Enright [16] | LLN: Quanjer [14] | LLN: Falaschetti [17] | |
|---|---|---|---|---|
COPD prevalence (N) | 244 (60%) | 142 (35%) | 167 (41%) | 175(43%) |
False positives (N) | 33 | 6 | 9 | 9 |
False negatives (N) | 36 | 111 | 89 | 81 |
Sensitivity | 85.4% | 55.1% | 64.0% | 67.2% |
Specificity | 79.1% | 96.2% | 94.3% | 94.3% |
Positive predictive value | 86.5% | 95.8% | 94.6% | 94.9% |
Negative predictive value | 77.6% | 57.8% | 62.6% | 64.8% |
Kappa coefficient | 0.64 (0.56; 0.71) | 0.46 (0.38; 0.53) | 0.53 (0.46; 0.60) | 0.57 (0.50; 0.64) |
P | < 0.001 | 0.006 | 0.053 |