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Table 1 Clinical, functional and inflammatory characteristics of bronchial secretions in patients with representative sputum samples* (n=133)

From: Specific IgA and metalloproteinase activity in bronchial secretions from stable chronic obstructive pulmonary disease patients colonized by Haemophilus influenzae

Patient characteristics  
Age (years), mean (SD) 70 (9)
Males, n (%) 124 (93)
Smoking pack-years, median (P25-P75) 67 (43-102)
Current smoker, n (%) 35 (27)
Exacerbation last year ≥1, n (%) 45 (34)
FEV1 post-BD % pred, mean (SD) 52 (16)
Sputum characteristics  
Neutrophils/ml ×106, median (P25-P75) 6.4 (1.7-17.1)
Neutrophils %, median (P25-P75) 72 (48-84)
IL-1β (pg/ml), median (P25-P75) 209 (52-695)
IL-6 (pg/ml), median (P25-P75) 124 (54-259)
IL-8 (×103) (pg/ml), median (P25-P75) 11 (4-16)
Colonized by PPMs, n (%) 39 (29.3)
Colonized by H. influenzae, n (%) 22 (17)
Bacterial load of H. influenzae x106 (cfu/ml), median (P25-P75) †* 5.4 (1-12)
  1. *Patients with representative sputum samples according to percentage of squamous cells≤20%.
  2. †* In patients with a positive culture for H. influenzae. Expressed as ×106 cfu/ml.
  3. Definition of abbreviations: SD = standard deviation; P25-P75 = percentile 25-percentile 75; BD = bronchodilator; FEV1= forced expiratory volume in 1 second; IL = interleukin; PPMs = potential pathogenic microorganisms; cfu = colony forming units.