Table 4 Characteristics of patients treated with ICS/LABA fixed combinations for at least 4 weeks before the 12-month follow-up visit
From: 1-year prospective real life monitoring of asthma control and quality of life in Italy
|  | Total n = 569 | BDP/F extrafine n = 301 | BUD/F n = 145 | FP/S n = 123 | Overall p-value |
|---|---|---|---|---|---|
Level of asthma control, n (%) | Â | Â | Â | Â | 0.001(1) |
  Fully controlled | 108 (19.0) | 77 (25.6) | 12 (8.3) | 19 (15.4) |  |
  Controlled | 351 (61.7) | 173 (57.5) | 102 (70.3) | 76 (61.8) |  |
  Partly controlled | 68 (12.0) | 31 (10.3) | 18 (12.4) | 19 (15.4) |  |
  Uncontrolled | 42 (7.4) | 20 (6.6) | 13 (9.0) | 9 (7.3) |  |
Current smokers, n (%) | 110 (19.3) | 69 (22.9) | 25 (17.2) | 16 (13.0) | 0.617 |
  Fully controlled | 25 (22.7) | 20 (29.0) | 3 (12.0) | 2 (12.5) | 0.135 |
  Controlled | 66 (60.0) | 39 (56.5) | 17 (68.0) | 10 (62.5) |  |
  Partly controlled | 12 (10.9) | 7 (10.1) | 3 (12.0) | 2 (12.5) |  |
  Uncontrolled | 7 (6.4) | 3 (4.4) | 2 (8.0) | 2 (12.5) |  |
ACT score, mean (SD) | 21.5 (3.4) | 22.0 (3.4) | 20.7 (3.6) | 21.3 (3.3) | <0.001(2) |
Improvement of 3 points in ACT score, n (%) | 493 (86.6) | 268 (89.0) | 116 (80.0) | 109 (88.6) | 0.024(3) |
Daily Dose of ICS, n | 537 | 287 | 141 | 122 | Â |
  Mean mcg (SD) | NA | 318.8 (114.3) | 651.1 (291.2) | 750.6 (371.7) | <0.001(4) |
Patients with exacerbation, n (%) (5) | 84 (14.8) | 40 (13.3) | 19 (13.1) | 25 (20.3) | 0.145 |