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Table 2 PESI for PE risk and diagnosis

From: The prognostic value of pulmonary embolism severity index in acute pulmonary embolism: a meta-analysis

First author, Year

PESI

Risk

Diagnosis

  

All-cause death

PE-related death

Adverse outcome

All-cause death

PE-related death

Adverse outcome

  

PESI low risk

PESI high risk

PESI low risk

PESI high risk

PESI low risk

PESI high risk

Sensitivity

Specific

Sensitivity

Specific

Sensitivity

Specific

Lankeit M, 2011

sPESI

1/198 (0.5%)

26/328 (7.9%)

0/198 (0.0%)

8/328 (2.4%)

2/198 (1.0%)

29/328 (8.8%)

0.963

0.395

1.000

0.382

0.935

0.396

Sánchez D, 2011

sPESI

7/407 (1.7%)

120/884 (13.6%)

2/407 (0.5%)

58/884 (6.6%)

Not mentioned

Not mentioned

0.945

0.344

0.967

0.329

N/A

N/A

Lankeit M, 2012

sPESI

0/165 (0.0%)

40/361 (11.1%)

Not mentioned

Not mentioned

3/165 (1.8%)

18/361 (5.0%)

1.000

0.340

N/A

N/A

0.857

0.321

Righini M, 2011

sPESI

1/165 (0.9%)

10/192 (5.2%)

1/165 (0.9%)

6/192 (3.0%)

Not mentioned

Not mentioned

0.909

0.474

0.857

0.469

N/A

N/A

Spirk D, 2011

sPESI

0/106 (0.0%)

16/263 (6.1%)

Not mentioned

Not mentioned

3/106 (2.9%)

21/263 (8.0%)

1.000

0.394

N/A

N/A

0.875

0.299

Vanni S, 2011

PESI

4/145 (2.8%)

34/318 (10.7%)

1/145 (0.7%)

24/318 (7.5%)

3/145 (2.1%)

29/318 (9.1%)

0.895

0.332

0.960

0.329

0.906

0.329

Venetz C, 2011

PESI

146/6332 (2.3%)

1234/9179 (14.1%)

Not mentioned

Not mentioned

63/6332 (1.0%)

275/9179 (3.0%)

0.894

0.438

N/A

N/A

0.814

0.417

Venetz C, 2011

sPESI

134/5715 (2.7%)

1236/9816 (13.1%)

Not mentioned

Not mentioned

69/5715 (1.2%)

275/9816 (2.8%)

0.902

0.394

N/A

N/A

0.799

0.372

Hariharan P, 2011

PESI

Not mentioned

Not mentioned

Not mentioned

Not mentioned

9/109 (8.3%)

54/136 (39.7%)

N/A

N/A

N/A

N/A

0.857

0.549

Jiménez D, 2011

PESI

Not mentioned

Not mentioned

1/199 (0.5%)

36/392 (9.2%)

Not mentioned

Not mentioned

N/A

N/A

0.973

0.357

N/A

N/A

Singanayagam A, 2011

PESI

1/197 (0.5%)

22/214 (10.3%)

Not mentioned

Not mentioned

Not mentioned

Not mentioned

0.957

0.505

N/A

N/A

N/A

N/A

Jiménez D, 2010 (Derivation Cohort)

PESI

89/4235 (2.1%)

857/6119 (14.0%)

Not mentioned

Not mentioned

Not mentioned

Not mentioned

0.906

0.411

N/A

N/A

N/A

N/A

Jiménez D, 2010 (Derivation Cohort)

sPESI

3/305 (1.0%)

75/690 (10.9%)

Not mentioned

Not mentioned

Not mentioned

Not mentioned

0.962

0.329

N/A

N/A

N/A

N/A

Jiménez D, 2010 (RIETE Cohort)

sPESI

28/2565 (1.1%)

404/4541 (8.9%)

Not mentioned

Not mentioned

Not mentioned

Not mentioned

0.935

0.380

N/A

N/A

N/A

N/A

Sam A, 2011

PESI

16/431 (3.7%)

103/775 (13.3%)

Not mentioned

Not mentioned

Not mentioned

Not mentioned

0.866

0.382

N/A

N/A

N/A

N/A

Sam A, 2011

sPESI

6/369 (1.6%)

113/837 (13.5%)

Not mentioned

Not mentioned

8/369 (2.2%)

34/837 (4.1%)

0.950

0.334

N/A

N/A

0.810

0.310

Chan CM, 2010

PESI

0/106 (0.0%)

9/196 (4.6%)

Not mentioned

Not mentioned

Not mentioned

Not mentioned

1.000

0.362

N/A

N/A

N/A

N/A

Singanayagam A, 2010

PESI

6/288 (2.1%)

38/297 (12.8%)

Not mentioned

Not mentioned

Not mentioned

Not mentioned

0.864

0.521

N/A

N/A

N/A

N/A

Moores L, 2010

PESI

2/191 (1.0%)

55/376 (14.6%)

1/191 (1.5%)

33/376 (8.8%)

Not mentioned

Not mentioned

0.965

0.371

0.971

0.356

N/A

N/A

Nordenholz K, 2011

PESI

0/91 (0.0%)

5/77 (6.5%)

Not mentioned

Not mentioned

Not mentioned

Not mentioned

1.000

0.588

N/A

N/A

N/A

N/A

Choi WH, 2009

PESI

3/39 (7.7%)

13/51 (25.5%)

Not mentioned

Not mentioned

Not mentioned

Not mentioned

0.813

0.486

N/A

N/A

N/A

N/A

Donzé J, 2008

PESI

2/186 (1.1%)

19/171 (11.1%)

Not mentioned

Not mentioned

Not mentioned

Not mentioned

0.905

0.548

N/A

N/A

N/A

N/A

Jiménez D, 2008

PESI

0/100 (0.0%)

12/218 (5.5%)

Not mentioned

Not mentioned

Not mentioned

Not mentioned

1.000

0.327

N/A

N/A

N/A

N/A

Jiménez D, 2007 (Validation Cohort)

PESI

2/216 (0.9%)

41/383 (10.7%)

Not mentioned

Not mentioned

6/216 (2.8%)

26/383 (6.8%)

0.953

0.385

N/A

N/A

0.813

0.370

Aujesky D, 2007

PESI

5/426 (1.2%)

53/573 (9.2%)

3/426 (0.7%)

18/573 (3.1%)

Not mentioned

Not mentioned

0.914

0.447

0.857

0.433

N/A

N/A

  1. Adverse outcome include nonfatal recurrent PE, nonfatal recurrent DVT, nonfatal bleeding, or delayed hemodynamic instability.