Figure 3
β 2 AR blocker propranolol abolishes formoterol-induced inhibition of DNA synthesis in human PAVSM cells. Cells were serum-deprived for 48 h, treated with 0.2, 2, 20 mM (R,R), (S,S), racemic formoterol, or diluent for 18 h in the presence (black bars) or absence (grey bars) of 10 μM propranolol followed by DNA synthesis analysis using the BrdU incorporation assay. Data represent mean values ± SE from two independent experiments, three repetitions per each experiment. *p < 0.001 for formoterol vs. formoterol + propranolol by ANOVA (Bonferroni-Dunn).