Table 2 Baseline physiologic measurements* in asthmatic and control subjects and in subgroups of these subjects.
From: Airway resistance at maximum inhalation as a marker of asthma and airway hyperresponsiveness
All subjects | Subgroups | |||||
|---|---|---|---|---|---|---|
Physiologic measurement | Nonasthmatic (n = 34) | Asthmatic (n = 35) | P value | Nonasthmatic methacholine nonresponders (n = 26) | Asthmatic methacholine responders (n = 31) | P value |
FEV1 % predicted | 95 ± 10 | 88 ± 11 | 0.009 | 97 ± 8 | 88 ± 11 | 0.002 |
FEV1/FVC % predicted | 100 ± 7 | 90 ± 9 | < 0.0001 | 102 ± 6 | 90 ± 9 | < 0.0001 |
FEF25-75 % predicted | 93 ± 20 | 69 ± 20 | < 0.0001 | 99 ±18 | 68 ±18 | < 0.0001 |
Rrs, cmH20/L/s | 2.21 ± 0.48 | 2.91 ± 0.99 | 0.0006 | 2.10 ±0.24 | 2.95 ±1.04 | 0.0005 |
Rmin, cmH20/L/s | 1.12 ± 0.31 | 1.39 ± 0.41 | 0.004 | 1.02 ± 0.24 | 1.41 ± 0.42 | 0.0001 |
Rmin, % predicted | 109 ± 19 | 134 ± 33 | 0.0004 | 102 ± 14 | 137 ± 33 | < 0.0001 |