Table 3 Comparison of the Distribution of S and Z Alleles in the INTDP cohort and the Biobank cohort
From: The prevalence of alpha-1 antitrypsin deficiency in Ireland
Phenotype | INTDP | Biobank | Total |
|---|---|---|---|
S versus other | |||
S alleles | 311 | 119 | 430 |
Other (including Z) | 5689 | 2081 | 7770 |
Total alleles | 6000 | 2200 | 8200 |
Z versus other (p < 0.001) | |||
Z alleles | 563 | 48 | 611 |
Other (including S) | 5437 | 2152 | 7589 |
Total alleles | 6000 | 2200 | 8200 |
Z versus S (p < 0.001) | |||
Z alleles | 563 | 48 | 611 |
S alleles | 311 | 119 | 430 |
Total alleles | 874 | 167 | 1041 |