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Table 3 Gene expression analysis of specific asthma genes and evidence for differential expression during human lung development (adjusted p < 0.001 cut off)

From: Expression analysis of asthma candidate genes during human and murine lung development

Human gene symbol

Probe id

Average expression

Adjusted p-value for differential expression

Beta coefficient†

NOD1

221073_s_at

7.6

7.0E-8

0.012

EDN1

222802_at

9.3

1.6E-6

0.026

EDN1

218995_s_at

8.6

4.4E-6

0.019

ROBO1

213194_at

10.2

1.5E-5

-0.009

IL4R

203233_at

7.3

3.3E-5

0.010

RORA

226682_at

8.2

3.5E-5

0.022

RORA

236266_at

5.2

5.2E-5

0.011

HPCAL1

212552_at

9.4

5.4E-5

0.012

HLA-DQB1

212998_x_at

4.8

1.5E-4

0.012

PLAUR

210845_s_at

5.9

2.0E-4

-0.008

IL2RB

205291_at

6.5

2.5E-4

0.007

CCL5

204655_at

4.7

2.6E-4

0.008

HPCAL1

205462_s_at

7.3

4.6E-4

0.013

TLR10

223751_x_at

4.1

4.9E-4

0.005

PDE10A

205501_at

6.4

6.3E-4

-0.011

CCL5

1405_i_at

4.1

9.9E-4

0.008

  1. * Adjusted p-value (B-H method) for differential expression over time.
  2. † The beta coefficient corresponds to the mean change in gene expression per day during the studied period (7-22 weeks of gestational age).