From: Expansion of CD4+CD25+helper T cells without regulatory function in smoking and COPD
Never smokers (NS) n = 9 | Smokers (S) n = 14 | COPD n = 9 | p | COPD ex-smokers n = 4 | COPD smokers n = 5 | p | |
---|---|---|---|---|---|---|---|
Total leukocytes | 21 (13-26) | 41 (34-52) | 25 (18-37) | P < 0.001 NS vs S | 20 (10-26) | 29 (22-52) | NS |
Macrophages | 19 (12-23) | 37 (31-48) | 22 (17-33) | P < 0.001 NS vs S P < 0.014 S vs COPD | 19 (9.6-22) | 27 (20-42) | P < 0.05 COPD ex-s vs COPD s |
Neutrophils | 0.2 (0.045-0.31) | 0.49 (0.23-1.1) | 0.19 (0.06-0.93) | NS | 0.36 (0.04-1.07) | 0.19 (0.07-5.2) | NS |
Lymphocytes | 1.7 (1.1-2.2) | 2.3 (1.5-3.9) | 1.5 (0.90-2.8) | NS | 1.5(0.8-2.2) | 1.5 (0.7-4.1) | NS |
Eosinophils | 0.08 (0-0.54) | 0.05 (0-0.3) | 0.06 (0.01-0.66) | NS | 0.015 (0.00-0.52) | 0.47 (0.05-0.96) | NS |
Mast cells | 0.06 (0.005-0.12) | 0.06 (0.03-0.10) | 0.03 (0.005-0.065) | NS | 0.005 (0.00-0.04) | 0.04 (0.02-0.10) | NS |