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Table 4 Prevalence of comorbidities among the "most costly" patients compared to the remainder.

From: Determinants of elevated healthcare utilization in patients with COPD

Comorbidity condition (ICD-9 codes)

Prevalence

  
 

"Most costly"* (n = 98)

The remainder (n = 291)

P value†

OR

95% CI

Hypertension (401 - 405)

74%

54%

<0.001

2.53

1.5 - 4.2

Myocardial infarct (410, 411)

70%

29%

<0.001

5.96

3.6 - 9.9

Connective tissue disease (710, 714, 725)

58%

57%

0.89

1.03

0.6 - 1.6

Congestive heart failure (398, 402, 428)

52%

14%

<0.001

6.81

4.1 - 11.4

Diabetes Mellitus (250)

50%

24%

<0.001

3.10

1.9 - 5.0

Moderate and severe renal disease (403, 404, 580 - 586)

37%

20%

0.001

2.38

1.4 - 3.9

Hemiplegia (342, 434, 436, 437)

29%

13%

<0.001

2.66

1.5 - 4.6

Peripheral vascular disease (440 - 447)

24%

13%

0.01

2.09

1.2 - 3.7

Cerebrovascular disease (430 - 433, 435)

23%

12%

0.01

2.17

1.2 - 3.9

Depression/Anxiety (296.2, 296.3, 311)

23%

15%

0.06

1.72

1.0 - 3.0

Peptic ulcer (531 - 534)

22%

15%

0.08

1.67

0.9 - 3.0

Diabetes Mellitus with organ damage (250.4 - 250.7)

21%

9%

0.001

2.78

1.5 - 5.2

Pulmonary hypertension (415, 416)

20%

7%

<0.001

3.67

1.9 - 7.2

Any tumor (140 - 195)

17%

10%

0.05

1.90

1.0 - 3.6

Obstructive sleep apnea (780.51, 780.53)

16%

9%

0.06

1.89

1.0 - 3.7

Mild liver disease (571, 573)

8%

3%

0.02

3.14

1.1 - 8.6

Moderate or severe liver disease (070, 570, 572)

7%

2%

0.01

4.40

1.4 - 14.2

Dementia (290, 291, 294)

3%

2%

0.42

1.81

0.4 - 7.7

Lymphoma (200, 202, 203)

1%

0%

0.42

2.99

0.2 - 48.4

Metastatic solid tumor (196 - 199)

1%

2%

0.63

0.59

0.1 - 5.1

Leukemia (204-208)

1%

1%

0.74

1.49

0.1-16.7

  1. None of the patients in this cohort had AIDS.
  2. * The "most costly" patients are those whose annualized utilization cost was within the upper 25 percentile; † Chi-square test.