Table 1 Clinical and physiological characteristics of the asthmatic children
From: Exhaled nitric oxide and clinical phenotypes of childhood asthma
Characteristics | N = 169 | |
|---|---|---|
Sex (male, %) | 104 (61%) | |
age, years | 10.5 ± 2.6 | |
height, cm | 142 ± 15 | |
weight, kg | 38 ± 15 | |
BMI, kg.m-2 | 18.0 ± 3.5 | |
Atopic status (skin prick test) | ||
negative | 27 (16%) | |
1 positive | 41 (24%) | |
> 1 positive | 101 (60%) | |
Tobacco exposure, n (%) | ||
maternal | 25 (15%) | |
paternal | 24 (14%) | |
paternal and maternal | 36 (21%) | |
Clinical events within past 3 months | ||
controlled, n (%) | 56 (33%) | |
partially or uncontrolled | 113 (67%) | |
number of days with symptoms, median [IQ] | 4 [0-12] | |
severe exacerbation | 42 (31%) | |
number of days with systemic steroid, median [IQ] | 0 [0-2] | |
Treatment | ||
beta-agonist on demand, n (%) | 82 (48%) | |
low ICS dose, n (%); mean ± SD dose, μg | 45 (27%); 154 ± 51 | |
medium ICS dose, n (%); mean ± SD dose, μg | 28 (17%); 357 ± 50 | |
high ICS dose, n (%); mean ± SD dose, μg | 14 (8%); 707 ± 154 | |
LABA, n (%) | 73 (43%) | |
Pulmonary function tests | Pre BD | Post BD |
sRaw, % predicted | 204 ± 45 | 126 ± 30 |
FEV1, % predicted | 97 ± 13 | 107 ± 12 |
FEV1/FVC, % | 78 ± 8 | 84 ± 6 |
FVC, % predicted | 105 ± 13 | 108 ± 12 |
FEF75-25%, % predicted | 71 ± 19 | 91 ± 20 |
FEF50%, % predicted | 71 ± 18 | 91 ± 19 |
TLC, % predicted | 104 ± 11 | 103 ± 10 |
FRC, % predicted | 103 ± 17 | 100 ± 15 |
RV, % predicted | 107 ± 28 | 93 ± 22 |
RV/TLC | 0.25 ± 0.06 | 0.22 ± 0.05 |
FEF50%/TLC | 0.71 ± 0.14 | 0.80 ± 0.18 |
FENO0.05 ppb, median [IQ] | 29 [15-48] | |