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Figure 6 | Respiratory Research

Figure 6

From: GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells

Figure 6

GDF-15 immunohistochemistry in a patient with PAH and Eisenmenger physiology. Intense signal for GDF 15 is noted in cells lining vascular channels. Inset shows prominent luminal staining of GDF-15 in endothelial cells (arrowhead). Note lower signal for GDF-15 in the connective tissue around the plexiform lesion, which probably represents GDF-15 bound to extracellular matrix (dashed arrows). Original magnifications: × 200; Inset × 400.

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Respiratory Research

ISSN: 1465-993X

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