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Figure 5 | Respiratory Research

Figure 5

From: GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells

Figure 5

GDF-15 immunohistochemistry in a plexiform lesion of a patient with IPAH. Immunohisto-chemical localization of GDF-15 protein in lung tissue of a patient with idiopathic pulmonary arterial hyperten-sion (IPAH). Intense signal for GDF-15 is seen in the cells of a plexiform lesion (P). Inset exhibits prominent luminal staining of GDF-15 in cells lining the vascular channel (arrow). Note the presence of GDF-15 in the endothelial cells of neigbouring small capillaries (arrowheads). Original magnifications: × 200; Inset × 400.

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