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Figure 10 | Respiratory Research

Figure 10

From: GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells

Figure 10

Upregulation of GDF-15 by shear stress. Human pulmonary microvascular endothelial cells (HPMEC) were exposed to laminar fluid flow (5 and 15 dynes/cm2) for 6 h. Expression of GDF-15 mRNA was assessed by quantitative RT-PCR. Data are presented as relative expression of GDF-15 mRNA normalized to two housekeeping genes (β-GUS and β-actin). Data from n = 5 each group are shown as mean ± SD. * = p < 0.05 compared to static control (0 dynes/cm2).

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Respiratory Research

ISSN: 1465-993X

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