Figure 2
From: Involvement of mast cells in monocrotaline-induced pulmonary hypertension in rats
Prevalence of pulmonary MCs in MCT-rats. Lung tissue from healthy and MCT-rats (that received single injection of saline and monocrotaline, respectively) were stained with toluidine blue (TB). The arrow indicates the positive signal (purple/violet stain) for MCs. (A) Representative photomicrographs of healthy (a) and MCT-injected (b) rat lungs are shown. (B) Total and (C) perivascular MC count of different vessel sizes are given. An IOG was determined for perivascular MCs and (D) IOG (in %) is shown. Each bar represents Mean ± SEM (n = 10). *p < 0.05 versus healthy rats/corresponding vessels of healthy rats. Scale = 20 μm.