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Figure 3 | Respiratory Research

Figure 3

From: Tenascin-C and alpha-smooth muscle actin positive cells are increased in the large airways in patients with COPD

Figure 3

The immunohistochemical expression of α-SMA, desmin and vimentin in bronchial biopsies from study subjects. The figures show representative microphotographs from each category. A: High power field of spindle shaped cells positive for α-SMA; scale bar = 0.05 mm. B: High power field of desmin positive spindle shaped cells; scale bar = 0.05 mm. C: Ring like structures of blood vessels positive for α-SMA; scale bar = 0.05 mm. D: Thick bundles of smooth muscle of the bronchial wall, staining for desmin; scale bar = 0.05 mm. E: Staining for vimentin from a case in which no α-SMA or desmin positive spindle shaped cells were found. Positive staining pattern in normal fibroblasts and lymphocytes of the subepithelial connective tissue; scale bar = 0.05 mm. F: A Negative control in which the primary antibody has been substituted with non-immune mouse serum; scale bar = 0.1 mm.

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