Figure 1
From: Matrix metalloproteinase-9 predicts pulmonary status declines in α1-antitrypsin deficiency
Timeline of repeated measures models for longitudinal analyses. Several repeated measures models were used to assess the longitudinal association of MMP-9 with the number (#) of subsequent COPD exacerbations or the subsequent changes (Δ) in various pulmonary status measures. The schedule of assessments for different pulmonary status measures varied in the REPAIR trial, necessitating different modeling time periods.