Figure 1
From: Diacylglycerol regulates acute hypoxic pulmonary vasoconstriction via TRPC6
No effect of 1-oleoyl-2-acetyl-sn-glycerol (OAG) on normoxic vascular tone in TRPC6-/- mouse lungs. The effect of OAG was investigated in isolated wild-type and TRPC6-/- mouse lungs. The OAG-induced vasoconstriction is represented as the increase in pulmonary artery pressure (ΔPAP) during normoxic ventilation. OAG was applied in increasing doses every 25 min. Data are derived from n = 5 and n = 4 wild-type and TRPC6-/-mice, respectively. * Significant differences compared to wild-type mice (p < 0.05).