Figure 6
From: Placenta growth factor and vascular endothelial growth factor B expression in the hypoxic lung
The actions of PlGF on endothelial cell wound healing. (A) Human pulmonary microvascular endothelial cell scratch assay in the presence of vehicle (panel 1), PlGF (40 ng/ml; panel 2) and PlGF (160 ng/ml; panel 3). (B) Mean (±SEM) percentage wound closure over a 24-hour period in the presence of PlGF under normoxic conditions. (C) Mean (±SEM) percentage wound closure over a 24-hour period in the presence of VEGFA (8 ng/ml)-PlGF (40 ng/ml) and VEGFA (8 ng/ml)-PlGF (160 ng/ml) in normoxic human pulmonary microvascular endothelial cells. * signifies a significant increase in wound healing compared to vehicle, †signifies significant difference from VEGFA alone (8 ng/ml) (P < 0.05, ANOVA, post hoc Student Newman Keuls). N = 6-9 per group.