Table 2 Univariate and multivariate odds ratio of asthma severity (GINA Step III and IV Combined) According to asthma risk factors and smoking variables
From: Greater severity of new onset asthma in allergic subjects who smoke: a 10-year longitudinal study
Variables | Univariate Odds Ratio (95% CI) | P value | Multivariate Odds Ratio (95% CI) | P value |
|---|---|---|---|---|
Gender | ||||
Female | 1.00 | |||
Male | 1.14 (0.58-2.23) | P = 0.71 | ||
Age | 1.07 (1.01-1.31) | P = 0.027 | ||
Family Hx of Atopy | 0.76 (0.37-1.58) | P = 0.46 | ||
Model 1 (n = 61) | 1.07 (0.31-3.66) | P = 0.92 | 1.19 (0.32-4.50) | P = 0.79 |
Passive Smoking | ||||
Model 2 (n = 152) | P = 0.043 | |||
Current or Former Smoker | 2.10 (1.03-4.31) | 1.93 (0.93-4.01) | P = 0.08 | |
Model 3 (n = 125) | ||||
Packs per Year | ||||
Never Smoker 0 | 1.00 | 1.00 | ||
1-10 packs 1 | 1.31 (0.43-4.03) | P = 0.63 | 1.47 (0.46-4.68) | P = 0.52 |
11-20 packs 2 | 3.51 (1.39-8.83) | P = 0.008 | 2.85 (1.09-7.46) | P = 0.032 |
>20 packs 3 | 7.67 (2.09-28.07) | P = 0.002 | 5.59 (1.44-21.67) | P = 0.013 |
Model 4 (n = 142) | ||||
Smoking Status | ||||
Never Smoker 0 | 1.00 | 1.00 | ||
Former Smoker 1 | 1.28 (0.39-4.22) | P = 0.69 | 1.26 (0.37-4.24) | P = 0.79 |
Current Smoker 2 | 3.07 (1.43-6.57) | P = 0.004 | 2.78 (1.28-6.08) | P = 0.009 |