Disturbance of the OPG/RANK/RANKL pathway and systemic inflammation in COPD patients with emphysema and osteoporosis

Table 1 Comparison of demographic parameters, pulmonary function results and Quality of Life Score between two COPD groups

Variables	COPD with normal BMD (n = 36)	COPD with low BMD (n = 44)	p-value
Age(yr)	65.5 ± 5.1	67.8 ± 5.2	0.049
BMI(kg/m²)	26.1 ± 3.6	23.5 ± 2.9	< 0.001
Smoking index(pack-yr)	28.1 ± 26.0	26.7 ± 21.6	0.79
CAT score	15.8 ± 9.6	21.0 ± 8.5	0.01
BODE index	3.3 ± 1.1	4.1 ± 1.2	0.26
FEV₁/FVC(%)	57.0 ± 10.1	53.9 ± 9.6	0.17
FEV₁ % predicted(%)	58.4 ± 19.2	52.8 ± 17.3	0.18

Data are mean (SD) unless otherwise stated.
COPD: chronic obstructive pulmonary disease, BMD: bone mineral density, BMI: body mass index, CAT: COPD Assessment Test, BODE index: body mass index, airflow obstruction, dyspnea, and exercise capacity index, FEV1: forced expiratory volume in one second

ISSN: 1465-993X