Table 3 Baseline values for biomarkers in which there was no significant difference between COPD subjects and either smoking or non-smoking controls.

Brain-derived neurotrophic growth factor (pg/mL)

200

36640.0 (17870.0)

37

35140.0 (14420.0)

0.656

37

35620.0 (10060.0)

0.381

CCL4 (pg/mL)

201

109.8 (86.0)

37

117.2 (70.0)

0.846

37

89.6 (86.2)

0.183

CCL23 (pg/mL)

201

501.8 (217.0)

37

443.0 (210.6)

0.483

37

468.0 (200.4)

0.178

CCL24 (pg/mL)

193

93.5 (124.0)

36

74.5 (100.0)

0.294

35

60.0 (61.5)

0.089

CXCL5 (pg/mL)

201

1415.0 (1065.0)

37

1265.0 (500.0)

0.144

37

1425.0 (975.0)

0.817

CXCL7 (pg/mL)*

199

34270367 (21359723)

37

36867340 (17597022)

0.582

36

33070725 (16762456)

0.425

CXCL11 (pg/mL)

200

19.8 (15.4)

36

18.4 (17.3)

0.488

36

16.8 (13.3)

0.249

Interferon-γ (pg/mL)

201

0.4 (0.0)

37

0.4 (0.0)

0.346

35

0.4 (0.0)

0.584

Interleukin-1β (pg/mL)

199

0.2 (0.0)

36

0.2 (0.2)

0.185

37

0.2 (0.0)

0.576

Interleukin-10 (pg/mL)

201

0.4 (0.0)

37

0.4 (0.0)

0.697

37

0.4 (0.0)

0.433

Interleukin-15 (pg/mL)

187

0.8 (0.0)

37

0.8 (0.0)

0.227

36

0.8 (0.0)

0.971

Interleukin-17 (pg/mL)

201

0.8 (0.0)

37

0.8 (0.0)

0.630

37

0.8 (0.0)

0.632

Interleukin-1 receptor antagonist (pg/mL)

193

217.4 (269.9)

36

204.6 (127.6)

0.609

34

139.0 (130.0)

0.056

Leptin (pg/mL)*

199

12857.5 (21025.5)

37

10074.8 (16770.9)

0.622

37

13103.6 (26107.2)

0.058

Tissue inhibitor of metalloproteinase-1 (pg/mL)

201

329500.0 (142100.0)

37

285800.0 (128900.0)

0.215

37

255100.0 (149400.0)

0.302

Transforming Growth Factor-α (pg/mL)

197

3.9 (10.0)

36

3.7 (9.7)

0.674

36

1.2 (5.4)

0.056

Tumor necrosis factor receptor type I (pg/mL)

201

1530.0 (655.0)

37

1525.0 (521.4)

0.999

37

1400.0 (600.0)

0.494

Tumor necrosis factor receptor type II (pg/mL)

196

1065.0 (545.0)

37

920.0 (525.0)

0.454

36

915.0 (537.5)

0.930

Tumor necrosis factor-α (pg/mL)

201

2.4 (0.0)

36

2.4 (0.0)

0.178

37

2.4 (0.0)

0.667